Coupling of canine serotonin 5-HT(1B) and 5-HT(1D) receptor subtypes to the formation of inositol phosphates by dual interactions with endogenous G(i/o) and recombinant G(alpha15) proteins.

Wurch, T; Pauwels, P J

Wurch, T; Pauwels, P J.

Affiliation

Wurch T; Department of Cellular and Molecular Biology, Centre de Recherche Pierre Fabre, Castres, France.

J Neurochem ; 75(3): 1180-9, 2000 Sep.

Article in En | MEDLINE | ID: mdl-10936201

Subject(s)

GTP-Binding Protein alpha Subunits, Gi-Go/metabolism; Heterotrimeric GTP-Binding Proteins/metabolism; Inositol Phosphates/metabolism; Receptors, Serotonin/physiology; Amino Acid Sequence; Animals; COS Cells; Cloning, Molecular; Dogs; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins/genetics; Humans; Ketanserin/metabolism; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin/chemistry; Receptors, Serotonin/genetics; Recombinant Proteins/metabolism; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin/metabolism; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Serotonin / GTP-Binding Protein alpha Subunits, Gi-Go / Heterotrimeric GTP-Binding Proteins / Inositol Phosphates Limits: Animals / Humans Language: En Journal: J Neurochem Year: 2000 Document type: Article Affiliation country: France Country of publication: United kingdom

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