A pilot study of low dose hydroxyurea as a novel resistance modulator in metastatic renal cell cancer.

Hao, D; Huan, S D; Stewart, D J; Segal, R J; Yau, J C

Hao, D; Huan, S D; Stewart, D J; Segal, R J; Yau, J C.

Affiliation

Hao D; Ottawa Regional Cancer Centre, Cancer Care Ontario, and University of Ottawa, Canada.

J Chemother ; 12(4): 360-6, 2000 Aug.

Article in En | MEDLINE | ID: mdl-10949987

Subject(s)

Antineoplastic Agents/pharmacology; Carcinoma, Renal Cell/metabolism; Drug Resistance, Neoplasm; Hydroxyurea/pharmacology; Kidney Neoplasms/metabolism; ATP Binding Cassette Transporter, Subfamily B/metabolism; Adult; Aged; Aged, 80 and over; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/therapeutic use; Carcinoma, Renal Cell/drug therapy; Carcinoma, Renal Cell/genetics; Carcinoma, Renal Cell/secondary; Chromosome Aberrations; Female; Humans; Hydroxyurea/administration & dosage; Hydroxyurea/therapeutic use; Kidney Neoplasms/drug therapy; Kidney Neoplasms/genetics; Kidney Neoplasms/pathology; Male; Middle Aged; Outcome Assessment, Health Care; Pilot Projects; Vinblastine/pharmacology; Vinblastine/therapeutic use

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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Drug Resistance, Neoplasm / Hydroxyurea / Kidney Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Chemother Journal subject: ANTINEOPLASICOS / TERAPIA POR MEDICAMENTOS Year: 2000 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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