Lonidamine and analogue AF2785 block the cyclic adenosine 3', 5'-monophosphate-activated chloride current and chloride secretion in the rat epididymis.

Gong, X D; Wong, Y L; Leung, G P; Cheng, C Y; Silvestrini, B; Wong, P Y

Gong, X D; Wong, Y L; Leung, G P; Cheng, C Y; Silvestrini, B; Wong, P Y.

Affiliation

Gong XD; Department of Physiology, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.

Biol Reprod ; 63(3): 833-8, 2000 Sep.

Article in En | MEDLINE | ID: mdl-10952928

Subject(s)

Benzyl Compounds/pharmacology; Chloride Channels/antagonists & inhibitors; Chlorides/metabolism; Cyclic AMP/pharmacology; Epididymis/physiology; Indazoles/pharmacology; Animals; Bicarbonates/administration & dosage; Chloride Channels/physiology; Chlorides/administration & dosage; Cystic Fibrosis Transmembrane Conductance Regulator/antagonists & inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator/physiology; Electric Conductivity; Epididymis/drug effects; Epithelial Cells/drug effects; Epithelial Cells/physiology; Male; Rats; Rats, Sprague-Dawley

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Collection: 01-internacional Database: MEDLINE Main subject: Benzyl Compounds / Chlorides / Chloride Channels / Cyclic AMP / Epididymis / Indazoles Limits: Animals Language: En Journal: Biol Reprod Year: 2000 Document type: Article Affiliation country: Hong Kong Country of publication: United States

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