Kinetics and equilibria in ligand binding by nitrophorins 1-4: evidence for stabilization of a nitric oxide-ferriheme complex through a ligand-induced conformational trap.

Andersen, J F; Ding, X D; Balfour, C; Shokhireva, T K; Champagne, D E; Walker, F A; Montfort, W R

Andersen, J F; Ding, X D; Balfour, C; Shokhireva, T K; Champagne, D E; Walker, F A; Montfort, W R.

Affiliation

Andersen JF; Departments of Biochemistry and Chemistry, University of Arizona, Tucson 85721, USA.

Biochemistry ; 39(33): 10118-31, 2000 Aug 22.

Article in En | MEDLINE | ID: mdl-10956000

Subject(s)

Carrier Proteins/metabolism; Hemeproteins/metabolism; Nitric Oxide/metabolism; Rhodnius; Salivary Proteins and Peptides/metabolism; Animals; Binding Sites; Carrier Proteins/chemistry; Carrier Proteins/genetics; Ferric Compounds/chemistry; Ferric Compounds/metabolism; Hemeproteins/chemistry; Hemeproteins/genetics; Histamine/metabolism; Kinetics; Ligands; Models, Chemical; Models, Molecular; Nitric Oxide/chemistry; Photolysis; Protein Structure, Tertiary; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Salivary Proteins and Peptides/chemistry; Salivary Proteins and Peptides/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Rhodnius / Salivary Proteins and Peptides / Carrier Proteins / Hemeproteins / Nitric Oxide Limits: Animals Language: En Journal: Biochemistry Year: 2000 Document type: Article Affiliation country: United States Country of publication: United States

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