The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells.

Coopman, P J; Do, M T; Barth, M; Bowden, E T; Hayes, A J; Basyuk, E; Blancato, J K; Vezza, P R; McLeskey, S W; Mangeat, P H; Mueller, S C

Coopman, P J; Do, M T; Barth, M; Bowden, E T; Hayes, A J; Basyuk, E; Blancato, J K; Vezza, P R; McLeskey, S W; Mangeat, P H; Mueller, S C.

Affiliation

Coopman PJ; Department of Cell Biology, and Vincent T. Lombardi Cancer Center, Georgetown University Medical School, Washington, DC 20007, USA.

Nature ; 406(6797): 742-7, 2000 Aug 17.

Article in En | MEDLINE | ID: mdl-10963601

Subject(s)

Breast Neoplasms/enzymology; Breast/enzymology; Enzyme Precursors/physiology; Protein-Tyrosine Kinases/physiology; Animals; Apoptosis; Breast/cytology; Breast Neoplasms/pathology; Catalysis; Cell Division/genetics; Cell Division/physiology; Cell Transformation, Neoplastic; Enzyme Precursors/genetics; Female; Genes, Tumor Suppressor; Humans; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Mice; Mice, Nude; Neoplasm Transplantation; Protein-Tyrosine Kinases/genetics; RNA, Messenger/metabolism; Syk Kinase; Transfection; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Breast / Breast Neoplasms / Enzyme Precursors Limits: Animals / Female / Humans Language: En Journal: Nature Year: 2000 Document type: Article Affiliation country: United States Country of publication: United kingdom

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