Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitro.

Takahashi, T; Hara, K; Inoue, H; Kawa, Y; Tokunaga, C; Hidayat, S; Yoshino, K; Kuroda, Y; Yonezawa, K

Takahashi, T; Hara, K; Inoue, H; Kawa, Y; Tokunaga, C; Hidayat, S; Yoshino, K; Kuroda, Y; Yonezawa, K.

Affiliation

Takahashi T; Biosignal Research Center, Kobe University, Kobe 657-8501, Japan.

Genes Cells ; 5(9): 765-75, 2000 Sep.

Article in En | MEDLINE | ID: mdl-10971657

Subject(s)

Phosphotransferases (Alcohol Group Acceptor)/metabolism; Protein Kinases; Ribosomal Protein S6 Kinases/metabolism; Amino Acid Sequence; Cell Line; Conserved Sequence; Eukaryotic Initiation Factor-4E; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Initiation Factors/metabolism; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor)/chemistry; Sequence Alignment; Sequence Deletion; Sirolimus/metabolism; Sirolimus/pharmacology; TOR Serine-Threonine Kinases

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Phosphotransferases (Alcohol Group Acceptor) / Ribosomal Protein S6 Kinases Limits: Humans Language: En Journal: Genes Cells Journal subject: BIOLOGIA MOLECULAR Year: 2000 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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