Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide.

Kestell, P; Zhao, L; Baguley, B C; Palmer, B D; Muller, G; Paxton, J W; Ching, L M

Kestell, P; Zhao, L; Baguley, B C; Palmer, B D; Muller, G; Paxton, J W; Ching, L M.

Affiliation

Kestell P; Auckland Cancer Society Research Centre, University of Auckland Medical School, New Zealand.

Cancer Chemother Pharmacol ; 46(2): 135-41, 2000.

Article in En | MEDLINE | ID: mdl-10972483

Subject(s)

Antineoplastic Agents/pharmacokinetics; Colonic Neoplasms/metabolism; Thalidomide/pharmacology; Xanthenes/pharmacokinetics; Xanthones; Animals; Antineoplastic Agents/blood; Area Under Curve; Bile/metabolism; Colonic Neoplasms/blood; Female; Half-Life; Mice; Mice, Inbred C57BL; Stereoisomerism; Time Factors; Tissue Distribution/drug effects; Xanthenes/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Thalidomide / Xanthenes / Colonic Neoplasms / Xanthones / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cancer Chemother Pharmacol Year: 2000 Document type: Article Affiliation country: New Zealand

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