A transactivation-deficient mouse model provides insights into Trp53 regulation and function.

Jimenez, G S; Nister, M; Stommel, J M; Beeche, M; Barcarse, E A; Zhang, X Q; O'Gorman, S; Wahl, G M

Jimenez, G S; Nister, M; Stommel, J M; Beeche, M; Barcarse, E A; Zhang, X Q; O'Gorman, S; Wahl, G M.

Affiliation

Jimenez GS; Gene Expression Laboratory, The Salk Institute, La Jolla, California, USA.

Nat Genet ; 26(1): 37-43, 2000 Sep.

Article in En | MEDLINE | ID: mdl-10973245

Subject(s)

Gene Expression Regulation, Neoplastic; Genes, p53; Transcriptional Activation; Tumor Suppressor Protein p53; Alleles; Animals; Apoptosis/genetics; DNA Damage/drug effects; Dactinomycin/pharmacology; Female; Mice; Mice, Transgenic; Models, Animal; Neoplasm Transplantation; Nucleic Acid Synthesis Inhibitors/pharmacology; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53/chemistry; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Transcriptional Activation / Genes, p53 / Tumor Suppressor Protein p53 Limits: Animals Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2000 Document type: Article Affiliation country: United States Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links