Principles of Wilms' tumor biology.
Urol Clin North Am
; 27(3): 423-33, viii, 2000 Aug.
Article
in En
| MEDLINE
| ID: mdl-10985142
ABSTRACT
The last few years have provided dramatic breakthroughs in understanding the genetic factors involved in Wilms' tumorigenesis and normal kidney development. The implications of these findings for the clinical management of children with Wilms' tumor are only now becoming apparent. Over 80% of patients with Wilms' tumor can be cured using contemporary multimodality therapy. As a consequence, the current NWTSG is attempting to intensify treatment for patients with poor prognostic features while decreasing therapy, and thereby adverse late effects, for patients with favorable prognosticators.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Genes, Wilms Tumor
/
Wilms Tumor
/
Kidney Neoplasms
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Urol Clin North Am
Year:
2000
Document type:
Article
Affiliation country:
Canada