The relationship between survival and cell proliferation index in squamous cell carcinoma of larynx.
Rev Laryngol Otol Rhinol (Bord)
; 121(2): 121-5, 2000.
Article
in En
| MEDLINE
| ID: mdl-10997073
Cell proliferation index is one of the most important factors in assessment of growth and progression of tumours. At present, the most suitable method of determining cell proliferation is by means of immunohistochemical techniques which use the monoclonal anti-body MIB-1 which reacts against Ki-67, a protein released only in the proliferation phases of the cell cycle. In this study, 44 patients diagnosed with squamous cell carcinoma of the larynx were analysed retrospectively and different macroscopic and microscopic parameters were assessed, such as MIB-1 in relation to the current status of the patient. A statistically significant relationship was found between the cell proliferation index, the histological grade of differentiation and the clinical evolution of the illness.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Carcinoma, Squamous Cell
/
Laryngeal Neoplasms
Type of study:
Observational_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Rev Laryngol Otol Rhinol (Bord)
Year:
2000
Document type:
Article
Affiliation country:
Spain
Country of publication:
France