Further leads on metabolic epidemiology of large bowel cancer.
Cancer Res
; 35(11 Pt. 2): 3403-6, 1975 Nov.
Article
in En
| MEDLINE
| ID: mdl-1104152
ABSTRACT
Studies in metabolic epidemiology have shown that the dietary intake of high fat affects the composition of the intestinal bacteria and their metabolic activity as well as the levels of certain neutral sterols and bile acids that may act as tumor promoters for the colon. A strong association has also been established between microbially modified bile acids and cholesterol metabolites and the risk of colon cancer among different populations. The patients with colon cancer had high concentrations of fecal bile acids and cholesterol metabolites compared with the controls. It remains to be shown whether this established association is causative in nature.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dietary Fats
/
Intestinal Neoplasms
/
Intestines
Type of study:
Etiology_studies
/
Screening_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Cancer Res
Year:
1975
Document type:
Article