Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity.

Tabrizi, S J; Orth, M; Wilkinson, J M; Taanman, J W; Warner, T T; Cooper, J M; Schapira, A H

Tabrizi, S J; Orth, M; Wilkinson, J M; Taanman, J W; Warner, T T; Cooper, J M; Schapira, A H.

Affiliation

Tabrizi SJ; University Department of Clinical Neurosciences, Royal Free and University College Medical School, London NW3 2PF, UK.

Hum Mol Genet ; 9(18): 2683-9, 2000 Nov 01.

Article in En | MEDLINE | ID: mdl-11063727

Subject(s)

Dopamine/pharmacology; Ecdysterone/analogs & derivatives; Genetic Predisposition to Disease/genetics; Mutation/genetics; Nerve Tissue Proteins/genetics; Parkinson Disease/genetics; Parkinson Disease/pathology; Blotting, Western; Cell Death/drug effects; Cell Line; Cell Size/drug effects; Drug-Related Side Effects and Adverse Reactions; Ecdysterone/pharmacology; Gene Expression; Humans; Immunohistochemistry; Male; Nerve Tissue Proteins/physiology; Neurons/drug effects; Neurons/pathology; Parkinson Disease, Secondary/chemically induced; Synucleins; Transfection; alpha-Synuclein

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Dopamine / Genetic Predisposition to Disease / Ecdysterone / Mutation / Nerve Tissue Proteins Type of study: Etiology_studies Limits: Humans / Male Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2000 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

Search on Google

Add to My VHL

XML

PubMed Links