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Total synthesis of (+)-7-deoxypancratistatin from furan.
Aceña, J L; Arjona, O; León, M L; Plumet, J.
Affiliation
  • Aceña JL; Departamento de Química Orgánica I, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain.
Org Lett ; 2(23): 3683-6, 2000 Nov 16.
Article in En | MEDLINE | ID: mdl-11073675
A new total synthesis of (+)-7-deoxypancratistatin 1 has been accomplished in 19 steps (8% overall yield) from two readly available compounds, furan and trans-1,2-bis(phenylsulfonyl)ethylene.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Plants, Medicinal / Amaryllidaceae Alkaloids / Furans / Isoquinolines / Antineoplastic Agents, Phytogenic Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2000 Document type: Article Affiliation country: Spain Country of publication: United States
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Collection: 01-internacional Database: MEDLINE Main subject: Plants, Medicinal / Amaryllidaceae Alkaloids / Furans / Isoquinolines / Antineoplastic Agents, Phytogenic Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2000 Document type: Article Affiliation country: Spain Country of publication: United States