The interleukin-6 receptor alpha-chain (CD126) is expressed by neoplastic but not normal plasma cells.

Rawstron, A C; Fenton, J A; Ashcroft, J; English, A; Jones, R A; Richards, S J; Pratt, G; Owen, R; Davies, F E; Child, J A; Jack, A S; Morgan, G

Rawstron, A C; Fenton, J A; Ashcroft, J; English, A; Jones, R A; Richards, S J; Pratt, G; Owen, R; Davies, F E; Child, J A; Jack, A S; Morgan, G.

Affiliation

Rawstron AC; Haematological Malignancy Diagnostic Service, Department of Haematology, Leeds General Infirmary, Leeds, United Kingdom.

Blood ; 96(12): 3880-6, 2000 Dec 01.

Article in En | MEDLINE | ID: mdl-11090073

Subject(s)

Bone Marrow Neoplasms/chemistry; Multiple Myeloma/metabolism; Plasmacytoma/chemistry; Receptors, Interleukin-6/biosynthesis; Aged; Aged, 80 and over; Antigens, CD/biosynthesis; Antigens, CD/immunology; Antigens, Neoplasm/biosynthesis; Biomarkers; Biomarkers, Tumor; Bone Marrow Cells/chemistry; Bone Marrow Cells/immunology; Bone Marrow Neoplasms/immunology; Bone Marrow Neoplasms/metabolism; Cytokine Receptor gp130; Flow Cytometry; Humans; Ki-67 Antigen/analysis; Membrane Glycoproteins/biosynthesis; Membrane Glycoproteins/immunology; Middle Aged; Neoplasm Proteins/biosynthesis; Paraproteinemias/metabolism; Plasma Cells/chemistry; Plasma Cells/immunology; Plasmacytoma/immunology; Protein Subunits; Receptors, Fibronectin/analysis; Receptors, Interleukin-6/immunology; beta 2-Microglobulin/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Plasmacytoma / Bone Marrow Neoplasms / Receptors, Interleukin-6 / Multiple Myeloma Limits: Aged / Aged80 / Humans / Middle aged Language: En Journal: Blood Year: 2000 Document type: Article Affiliation country: United kingdom

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