Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states.

Kajander, O A; Rovio, A T; Majamaa, K; Poulton, J; Spelbrink, J N; Holt, I J; Karhunen, P J; Jacobs, H T

Kajander, O A; Rovio, A T; Majamaa, K; Poulton, J; Spelbrink, J N; Holt, I J; Karhunen, P J; Jacobs, H T.

Affiliation

Kajander OA; Institute of Medical Technology, University of Tampere and Tampere University Hospital, Tampere, Finland.

Hum Mol Genet ; 9(19): 2821-35, 2000 Nov 22.

Article in En | MEDLINE | ID: mdl-11092758

Subject(s)

DNA, Mitochondrial/genetics; Mitochondria/genetics; Mitochondria/pathology; Recombination, Genetic/genetics; Adult; Aged; Aged, 80 and over; Aging/genetics; Base Sequence; Chromosome Breakage/genetics; Cloning, Molecular; DNA, Mitochondrial/chemistry; DNA, Mitochondrial/metabolism; Electrophoresis, Agar Gel; Female; Fluorescence; Gene Dosage; Gene Duplication; Humans; Male; Middle Aged; Mutagenesis/genetics; Myocardium/metabolism; Myocardium/pathology; Nucleic Acid Conformation; Organ Specificity; Oxidative Stress/genetics; Polymerase Chain Reaction; Sequence Deletion/genetics; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Recombination, Genetic / DNA, Mitochondrial / Mitochondria Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2000 Document type: Article Affiliation country: Finland Country of publication: United kingdom

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