Dominant late-onset retinal degeneration with regional variation of sub-retinal pigment epithelium deposits, retinal function, and photoreceptor degeneration.

Milam, A H; Curcio, C A; Cideciyan, A V; Saxena, S; John, S K; Kruth, H S; Malek, G; Heckenlively, J R; Weleber, R G; Jacobson, S G

Milam, A H; Curcio, C A; Cideciyan, A V; Saxena, S; John, S K; Kruth, H S; Malek, G; Heckenlively, J R; Weleber, R G; Jacobson, S G.

Affiliation

Milam AH; Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Ophthalmology ; 107(12): 2256-66, 2000 Dec.

Article in En | MEDLINE | ID: mdl-11097607

Subject(s)

Eye Diseases, Hereditary/pathology; Photoreceptor Cells, Vertebrate/pathology; Pigment Epithelium of Eye/pathology; Retina/physiology; Retinal Degeneration/pathology; Adult; Aged; Aged, 80 and over; Apolipoproteins/metabolism; Bruch Membrane/pathology; Dark Adaptation; Electroretinography; Eye Diseases, Hereditary/genetics; Eye Diseases, Hereditary/metabolism; Eye Diseases, Hereditary/physiopathology; Female; Filipin/metabolism; Humans; Immunohistochemistry; Male; Middle Aged; Pedigree; Photoreceptor Cells, Vertebrate/metabolism; Photoreceptor Cells, Vertebrate/ultrastructure; Pigment Epithelium of Eye/metabolism; Pigment Epithelium of Eye/ultrastructure; Retinal Degeneration/genetics; Retinal Degeneration/metabolism; Retinal Degeneration/physiopathology; Tissue Donors; Visual Acuity; Visual Fields

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Collection: 01-internacional Database: MEDLINE Main subject: Pigment Epithelium of Eye / Retina / Retinal Degeneration / Eye Diseases, Hereditary / Photoreceptor Cells, Vertebrate Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Ophthalmology Year: 2000 Document type: Article Affiliation country: United States Country of publication: United States

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