Interferon alpha prevents spontaneous apoptosis of clonal Th2 cells associated with chronic hypereosinophilia.

Schandené, L; Roufosse, F; de Lavareille, A; Stordeur, P; Efira, A; Kennès, B; Cogan, E; Goldman, M

Schandené, L; Roufosse, F; de Lavareille, A; Stordeur, P; Efira, A; Kennès, B; Cogan, E; Goldman, M.

Affiliation

Schandené L; Department of Immunology, Hôpital Erasme, Brussels, Belgium.

Blood ; 96(13): 4285-92, 2000 Dec 15.

Article in En | MEDLINE | ID: mdl-11110703

Subject(s)

Apoptosis/drug effects; Hypereosinophilic Syndrome/immunology; Interferon-alpha/pharmacology; Th2 Cells/drug effects; Adult; Cells, Cultured; Chronic Disease; Clone Cells/drug effects; Fas Ligand Protein; Female; Gene Expression Regulation; Genes, bcl-2; Humans; Hypereosinophilic Syndrome/drug therapy; Hypereosinophilic Syndrome/pathology; Immunologic Memory; Immunophenotyping; Interferon alpha-2; Interferon-alpha/therapeutic use; Interleukin-2/pharmacology; Intracellular Membranes/drug effects; Membrane Glycoproteins/pharmacology; Mitochondria/drug effects; Permeability/drug effects; Proto-Oncogene Proteins c-bcl-2/biosynthesis; Proto-Oncogene Proteins c-bcl-2/genetics; Protoporphyrins/pharmacology; Reactive Oxygen Species; Recombinant Proteins/pharmacology; Superoxides/metabolism; bcl-X Protein; fas Receptor/physiology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Interferon-alpha / Apoptosis / Hypereosinophilic Syndrome / Th2 Cells Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans Language: En Journal: Blood Year: 2000 Document type: Article Affiliation country: Belgium Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links