Toxicity and genotoxicity of antimalarial alkaloid rich extracts derived from Mitragyna inermis O. Kuntze and Nauclea latifolia.

Traore, F; Gasquet, M; Laget, M; Guiraud, H; Di Giorgio, C; Azas, N; Doumbo, O; Timon-David, P

Traore, F; Gasquet, M; Laget, M; Guiraud, H; Di Giorgio, C; Azas, N; Doumbo, O; Timon-David, P.

Affiliation

Traore F; P.A.O.N. (EA 864) Université de la Méditerranée, Faculté de Pharmacie, Marseille, France.

Phytother Res ; 14(8): 608-11, 2000 Dec.

Article in En | MEDLINE | ID: mdl-11113997

Subject(s)

Alkaloids/toxicity; Antimalarials/toxicity; DNA Damage; Monocytes/drug effects; Plant Extracts/toxicity; Plants, Medicinal/toxicity; Animals; Carbocyanines/chemistry; Comet Assay; Flow Cytometry; Humans; Kidney/chemistry; Kinetics; Liver/chemistry; Lymphocytes/chemistry; Mali; Medicine, African Traditional; Membrane Potentials; Mice; Microscopy, Fluorescence; Monocytes/cytology; Mutagenicity Tests; Salmonella typhimurium/drug effects; Salmonella typhimurium/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Plants, Medicinal / DNA Damage / Plant Extracts / Monocytes / Alkaloids / Antimalarials Limits: Animals / Humans Country/Region as subject: Africa Language: En Journal: Phytother Res Journal subject: TERAPIAS COMPLEMENTARES Year: 2000 Document type: Article Affiliation country: France Country of publication: United kingdom

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