B7 requirements for primary and secondary protein- and polysaccharide-specific Ig isotype responses to Streptococcus pneumoniae.

Wu, Z Q; Khan, A Q; Shen, Y; Schartman, J; Peach, R; Lees, A; Mond, J J; Gause, W C; Snapper, C M

Wu, Z Q; Khan, A Q; Shen, Y; Schartman, J; Peach, R; Lees, A; Mond, J J; Gause, W C; Snapper, C M.

Affiliation

Wu ZQ; Departments of. Pathology and Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

J Immunol ; 165(12): 6840-8, 2000 Dec 15.

Article in En | MEDLINE | ID: mdl-11120807

Subject(s)

Antigens, CD/physiology; B7-1 Antigen/physiology; Immunization, Secondary; Immunoconjugates; Immunoglobulin Isotypes/biosynthesis; Membrane Glycoproteins/physiology; Polysaccharides, Bacterial/immunology; Streptococcus pneumoniae/immunology; Abatacept; Animals; Antibodies, Blocking/administration & dosage; Antibodies, Monoclonal/administration & dosage; Antigens, CD/immunology; Antigens, CD/metabolism; Antigens, Differentiation/administration & dosage; B7-1 Antigen/immunology; B7-1 Antigen/metabolism; B7-2 Antigen; Bacterial Proteins/immunology; CD28 Antigens/genetics; CD28 Antigens/physiology; CTLA-4 Antigen; Dose-Response Relationship, Immunologic; Epitopes/immunology; Immunoglobulin Fc Fragments/administration & dosage; Immunoglobulin G/biosynthesis; Immunoglobulin Isotypes/blood; Immunologic Memory; Immunosuppressive Agents/administration & dosage; Injections, Intraperitoneal; Kinetics; Ligands; Membrane Glycoproteins/antagonists & inhibitors; Membrane Glycoproteins/immunology; Membrane Glycoproteins/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylcholine/immunology; Polysaccharides, Bacterial/administration & dosage; Recombinant Fusion Proteins/administration & dosage; Recombinant Fusion Proteins/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Streptococcus pneumoniae / Immunoglobulin Isotypes / Membrane Glycoproteins / Antigens, CD / Immunization, Secondary / B7-1 Antigen / Immunoconjugates Language: En Journal: J Immunol Year: 2000 Document type: Article Affiliation country: United States Country of publication: United States

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