Induction of early growth response-1 gene expression by calmodulin antagonist trifluoperazine through the activation of Elk-1 in human fibrosarcoma HT1080 cells.

Shin, S Y; Kim, S Y; Kim, J H; Min, D S; Ko, J; Kang, U G; Kim, Y S; Kwon, T K; Han, M Y; Kim, Y H; Lee, Y H

Shin, S Y; Kim, S Y; Kim, J H; Min, D S; Ko, J; Kang, U G; Kim, Y S; Kwon, T K; Han, M Y; Kim, Y H; Lee, Y H.

Affiliation

Shin SY; Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, Daegu 705-717, South Korea.

J Biol Chem ; 276(11): 7797-805, 2001 Mar 16.

Article in En | MEDLINE | ID: mdl-11121417

Subject(s)

Calmodulin/antagonists & inhibitors; DNA-Binding Proteins/genetics; Fibrosarcoma/metabolism; Gene Expression Regulation/drug effects; Immediate-Early Proteins; MAP Kinase Kinase Kinase 1; Proto-Oncogene Proteins/physiology; Transcription Factors/genetics; Trifluoperazine/pharmacology; Chlorpromazine/pharmacology; Early Growth Response Protein 1; Fibrosarcoma/pathology; Humans; Mitogen-Activated Protein Kinase 1/physiology; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases/physiology; Promoter Regions, Genetic; Protein Kinase C/physiology; Protein Serine-Threonine Kinases/physiology; Tumor Cells, Cultured; ets-Domain Protein Elk-1

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Trifluoperazine / Calmodulin / Gene Expression Regulation / Proto-Oncogene Proteins / Immediate-Early Proteins / MAP Kinase Kinase Kinase 1 / DNA-Binding Proteins / Fibrosarcoma Limits: Humans Language: En Journal: J Biol Chem Year: 2001 Document type: Article Affiliation country: South Korea Country of publication: United States

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