Diterpene from Baccharis trimera with a relaxant effect on rat vascular smooth muscle.
Phytochemistry
; 55(6): 617-9, 2000 Nov.
Article
in En
| MEDLINE
| ID: mdl-11130673
ABSTRACT
A bioassay monitored fractionation of a chloroform extract from the aerial parts of Baccharis trimera yielded a mixture that blocked the Ca2+-induced contractions of KCl- depolarized rat portal vein preparations. Pharmacological tests of two pure compounds isolated from the mixture revealed the dilactonic clerodane diterpene as the active compound.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Asteraceae
/
Diterpenes
/
Muscle Relaxation
/
Muscle, Smooth, Vascular
Limits:
Animals
Language:
En
Journal:
Phytochemistry
Year:
2000
Document type:
Article
Affiliation country:
Brazil
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM