1,8-Naphthyridines IV. 9-substituted N,N-dialkyl-5-(alkylamino or cycloalkylamino) [1,2,4]triazolo[4,3-a][1, 8]naphthyridine-6-carboxamides, new compounds with anti-aggressive and potent anti-inflammatory activities.

Roma, G; Di Braccio, M; Grossi, G; Mattioli, F; Ghia, M

Roma, G; Di Braccio, M; Grossi, G; Mattioli, F; Ghia, M.

Affiliation

Roma G; Dipartimento di Scienze Farmaceutiche, Università di Genova, Viale Benedetto XV 3, 16132, Genoa, Italy. roma@unige.it

Eur J Med Chem ; 35(11): 1021-35, 2000 Nov.

Article in En | MEDLINE | ID: mdl-11137230

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Naphthyridines/pharmacology; Aggression/drug effects; Animals; Anti-Inflammatory Agents, Non-Steroidal/chemistry; Dose-Response Relationship, Drug; Male; Mice; Naphthyridines/chemistry; Rats; Rats, Sprague-Dawley; Spectrum Analysis; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Naphthyridines Limits: Animals Language: En Journal: Eur J Med Chem Year: 2000 Document type: Article Affiliation country: Italy

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