Suppressive effect of topically applied CX-659S, a novel diaminouracil derivative, on the contact hypersensitivity reaction in various animal models.

Goto, Y; Inoue, Y; Tsuchiya, M; Isobe, M; Ueno, T; Uchi, H; Furue, M; Hayashi, H

Goto, Y; Inoue, Y; Tsuchiya, M; Isobe, M; Ueno, T; Uchi, H; Furue, M; Hayashi, H.

Affiliation

Goto Y; Pharmaceutical and Biotechnology Laboratory, Japan Energy Corporation, Toda-shi, Saitama, Japan.

Int Arch Allergy Immunol ; 123(4): 341-8, 2000 Dec.

Article in En | MEDLINE | ID: mdl-11146392

Subject(s)

Dermatitis, Contact/drug therapy; Immunosuppressive Agents/administration & dosage; Uracil/administration & dosage; Administration, Topical; Animals; Base Sequence; DNA Primers/genetics; Dermatitis, Contact/etiology; Dermatitis, Contact/pathology; Dinitrochlorobenzene/immunology; Dinitrochlorobenzene/toxicity; Disease Models, Animal; Guinea Pigs; Humans; Interleukin-1/genetics; Male; Mice; Mice, Inbred ICR; Oxazolone/immunology; Oxazolone/toxicity; RNA, Messenger/genetics; RNA, Messenger/metabolism; Tumor Necrosis Factor-alpha/genetics; Uracil/analogs & derivatives

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Collection: 01-internacional Database: MEDLINE Main subject: Uracil / Dermatitis, Contact / Immunosuppressive Agents Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Int Arch Allergy Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2000 Document type: Article Affiliation country: Japan Country of publication: Switzerland

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