Effects of an antibody to vascular endothelial growth factor receptor-2 on survival, tumor vascularity, and apoptosis in a murine model of colon carcinomatosis.

Shaheen, R M; Tseng, W W; Vellagas, R; Liu, W; Ahmad, S A; Jung, Y D; Reinmuth, N; Drazan, K E; Bucana, C D; Hicklin, D J; Ellis, L M

Shaheen, R M; Tseng, W W; Vellagas, R; Liu, W; Ahmad, S A; Jung, Y D; Reinmuth, N; Drazan, K E; Bucana, C D; Hicklin, D J; Ellis, L M.

Affiliation

Shaheen RM; Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

Int J Oncol ; 18(2): 221-6, 2001 Feb.

Article in En | MEDLINE | ID: mdl-11172585

Subject(s)

Antibodies/pharmacology; Carcinoma/drug therapy; Colonic Neoplasms/drug therapy; Neovascularization, Pathologic/drug therapy; Peritoneal Neoplasms/drug therapy; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors; Receptors, Growth Factor/antagonists & inhibitors; Animals; Antibodies/therapeutic use; Apoptosis/drug effects; Apoptosis/physiology; Carcinoma/mortality; Cell Division/drug effects; Cell Division/physiology; Colonic Neoplasms/blood supply; Colonic Neoplasms/mortality; Endothelium, Vascular/drug effects; Male; Mice; Mice, Inbred BALB C; Peritoneal Neoplasms/mortality; Receptors, Vascular Endothelial Growth Factor; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Peritoneal Neoplasms / Carcinoma / Receptors, Growth Factor / Receptor Protein-Tyrosine Kinases / Colonic Neoplasms / Antibodies / Neovascularization, Pathologic Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2001 Document type: Article Affiliation country: United States Country of publication: Greece

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