The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase.

Hall, A G; Hamilton, P; Minto, L; Coulthard, S A

Hall, A G; Hamilton, P; Minto, L; Coulthard, S A.

Affiliation

Hall AG; Leukaemia Research Fund Laboratory, University of Newcastle Upon Tyne, Newcastle Upon Tyne, UK. a.g.hall@ncl.ac.uk

J Biochem Biophys Methods ; 47(1-2): 65-71, 2001 Jan 30.

Article in En | MEDLINE | ID: mdl-11179762

Subject(s)

Chromatography, High Pressure Liquid/methods; DNA Mutational Analysis/methods; Methyltransferases/genetics; Antineoplastic Agents/adverse effects; Antineoplastic Agents/metabolism; Humans; Immunosuppressive Agents/adverse effects; Immunosuppressive Agents/metabolism; Methyltransferases/blood; Nucleic Acid Denaturation; Point Mutation; Polymerase Chain Reaction

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Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Chromatography, High Pressure Liquid / Methyltransferases Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Biochem Biophys Methods Year: 2001 Document type: Article Affiliation country: United kingdom

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