Oligo-amenorrheic long-distance runners may lose more bone in spine than in femur.
Med Sci Sports Exerc
; 33(1): 15-21, 2001 Jan.
Article
in En
| MEDLINE
| ID: mdl-11194101
ABSTRACT
PURPOSE:
Strenuous training can be associated with amenorrhea leading to amenorrhea-related accelerated bone loss. Insufficient calorie energy, calcium, and/or protein intakes can also be frequently encountered in women with intense training, possibly contributing to bone loss. Long-distance runners with or without regular menses (age range 19-37 yr) were prospectively studied.METHODS:
Changes in areal bone mineral density (BMD) were measured at 1-yr interval.RESULTS:
Among 10 eumenorrheic, 11 oligo-amenorrheic, and 9 oral contraceptive users, there was no difference in energy, calcium, or protein intakes. Baseline BMD values were significantly lower in the oligo-amenorrheic group than in the two others at the level of lumbar spine (anteroposterior view 0.941+/-0.039 in oligo-amenorrheic vs 1.077+/-0.029 or 1.051 +/-0.017 g x cm(-2), P < 0.005, in the eumenorrheic and contraceptive user groups, respectively) but not in weight-bearing bone such as proximal and midshaft femur. Over a 1-yr interval, during which the three groups did not differ in terms of running distances and dietary intakes, oligo-amenorrheic women displayed a significant decrease in lumbar spine BMD in lateral view (-0.049+/-0.012 in oligo-amenorrheic vs -0.001+/-0.013 and 0.014+/-0.012 g x cm(-2), p < 0.005, in the eumenorrheic and contraceptive user groups, respectively). We did not detect any significant change in femoral neck, trochanter, or midshaft BMD.CONCLUSIONS:
Oligo-amenorrhea in long-distance runners, with adequate dietary intakes, was associated with a decrease in BMD affecting more the lumbar spine than the proximal and midshaft femur during a 1-yr follow-up.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Oligomenorrhea
/
Osteoporosis
/
Running
/
Spine
/
Femur
/
Amenorrhea
Limits:
Adult
/
Female
/
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Med Sci Sports Exerc
Year:
2001
Document type:
Article
Affiliation country:
Switzerland