3-Deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates and carbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and cancer cell growth.
Bioorg Med Chem Lett
; 11(2): 173-6, 2001 Jan 22.
Article
in En
| MEDLINE
| ID: mdl-11206452
3-Modified D-myo-inositol imidazolyl ether lipid phosphates and a carbonate were synthesized and evaluated as inhibitors of P13-K and Akt. These data are presented along with IC50 values for the inhibition of the growth of three cancer cell lines.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phospholipid Ethers
/
Protein Serine-Threonine Kinases
/
Phosphoinositide-3 Kinase Inhibitors
/
Antineoplastic Agents
Limits:
Animals
/
Humans
Language:
En
Journal:
Bioorg Med Chem Lett
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2001
Document type:
Article
Affiliation country:
United States
Country of publication:
United kingdom