Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer.

Rischin, D; Peters, L; Hicks, R; Hughes, P; Fisher, R; Hart, R; Sexton, M; D'Costa, I; von Roemeling, R

Rischin, D; Peters, L; Hicks, R; Hughes, P; Fisher, R; Hart, R; Sexton, M; D'Costa, I; von Roemeling, R.

Affiliation

Rischin D; Division of Hematology and Medical Oncology, and Statistical Centre, Peter MacCallum Cancer Institute, Melbourne, Australia. drischin@petermarc.unimelb.edu.au

J Clin Oncol ; 19(2): 535-42, 2001 Jan 15.

Article in En | MEDLINE | ID: mdl-11208848

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Carcinoma, Squamous Cell/drug therapy; Carcinoma, Squamous Cell/radiotherapy; Head and Neck Neoplasms/drug therapy; Head and Neck Neoplasms/radiotherapy; Misonidazole/analogs & derivatives; Adult; Aged; Carcinoma, Squamous Cell/diagnostic imaging; Carcinoma, Squamous Cell/metabolism; Cell Hypoxia; Cisplatin/administration & dosage; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Administration Schedule; Fluorodeoxyglucose F18; Head and Neck Neoplasms/diagnostic imaging; Head and Neck Neoplasms/metabolism; Humans; Middle Aged; Radiation-Sensitizing Agents/administration & dosage; Radiopharmaceuticals; Survival Analysis; Tirapazamine; Tomography, Emission-Computed; Triazines/administration & dosage

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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Antineoplastic Combined Chemotherapy Protocols / Head and Neck Neoplasms / Misonidazole Limits: Adult / Aged / Humans / Middle aged Language: En Journal: J Clin Oncol Year: 2001 Document type: Article Affiliation country: Australia

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