15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells.

Shappell, S B; Gupta, R A; Manning, S; Whitehead, R; Boeglin, W E; Schneider, C; Case, T; Price, J; Jack, G S; Wheeler, T M; Matusik, R J; Brash, A R; Dubois, R N

Shappell, S B; Gupta, R A; Manning, S; Whitehead, R; Boeglin, W E; Schneider, C; Case, T; Price, J; Jack, G S; Wheeler, T M; Matusik, R J; Brash, A R; Dubois, R N.

Affiliation

Shappell SB; Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2561, USA. scott.shappell@mcmail.vanderbilt.edu

Cancer Res ; 61(2): 497-503, 2001 Jan 15.

Article in En | MEDLINE | ID: mdl-11212240

Subject(s)

Cell Division/drug effects; Hydroxyeicosatetraenoic Acids/pharmacology; Prostatic Neoplasms/genetics; Receptors, Cytoplasmic and Nuclear/genetics; Thiazolidinediones; Transcription Factors/genetics; Agar/pharmacology; Arachidonate 15-Lipoxygenase/genetics; Arachidonate 15-Lipoxygenase/metabolism; Blotting, Northern; Catalysis; Culture Media/pharmacology; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic/drug effects; Humans; Hydroxyeicosatetraenoic Acids/metabolism; Isoenzymes/genetics; Isoenzymes/metabolism; Luciferases/drug effects; Luciferases/genetics; Luciferases/metabolism; Male; Prostatic Neoplasms/pathology; RNA, Messenger/drug effects; RNA, Messenger/genetics; RNA, Messenger/metabolism; Receptors, Cytoplasmic and Nuclear/metabolism; Recombinant Fusion Proteins/drug effects; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Rosiglitazone; Thiazoles/pharmacology; Transcription Factors/metabolism; Transcription, Genetic/drug effects; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Transcription Factors / Cell Division / Hydroxyeicosatetraenoic Acids / Receptors, Cytoplasmic and Nuclear / Thiazolidinediones Limits: Humans / Male Language: En Journal: Cancer Res Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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