Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis.

Shih, I M; Zhou, W; Goodman, S N; Lengauer, C; Kinzler, K W; Vogelstein, B

Shih, I M; Zhou, W; Goodman, S N; Lengauer, C; Kinzler, K W; Vogelstein, B.

Affiliation

Shih IM; Johns Hopkins Oncology Center, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA.

Cancer Res ; 61(3): 818-22, 2001 Feb 01.

Article in En | MEDLINE | ID: mdl-11221861

Subject(s)

Adenoma/genetics; Allelic Imbalance; Colorectal Neoplasms/genetics; Adenoma/pathology; Colorectal Neoplasms/pathology; DNA Primers; DNA, Neoplasm/genetics; Genetic Markers/genetics; Humans; Polymerase Chain Reaction/methods; Polymorphism, Single Nucleotide; Probability

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Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Adenoma / Allelic Imbalance Limits: Humans Language: En Journal: Cancer Res Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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