Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke.

Lees, K R; Sharma, A K; Barer, D; Ford, G A; Kostulas, V; Cheng, Y F; Odergren, T

Lees, K R; Sharma, A K; Barer, D; Ford, G A; Kostulas, V; Cheng, Y F; Odergren, T.

Affiliation

Lees KR; University Department of Medicine and Therapeutics, Western Infirmary, Glasgow, UK.

Stroke ; 32(3): 675-80, 2001 Mar.

Article in En | MEDLINE | ID: mdl-11239186

Subject(s)

Neuroprotective Agents/pharmacokinetics; Nitrogen Oxides/pharmacokinetics; Stroke/drug therapy; Trypsin Inhibitor, Kunitz Soybean; Adult; Aged; Aged, 80 and over; Benzenesulfonates; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Membrane Glycoproteins/urine; Metabolic Clearance Rate; Middle Aged; Neuroprotective Agents/administration & dosage; Neuroprotective Agents/adverse effects; Nitrogen Oxides/administration & dosage; Nitrogen Oxides/adverse effects; Severity of Illness Index; Stroke/diagnosis; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Trypsin Inhibitor, Kunitz Soybean / Neuroprotective Agents / Stroke / Nitrogen Oxides Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Stroke Year: 2001 Document type: Article Affiliation country: United kingdom

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