Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.

Lindsay, E A; Vitelli, F; Su, H; Morishima, M; Huynh, T; Pramparo, T; Jurecic, V; Ogunrinu, G; Sutherland, H F; Scambler, P J; Bradley, A; Baldini, A

Lindsay, E A; Vitelli, F; Su, H; Morishima, M; Huynh, T; Pramparo, T; Jurecic, V; Ogunrinu, G; Sutherland, H F; Scambler, P J; Bradley, A; Baldini, A.

Affiliation

Lindsay EA; Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.

Nature ; 410(6824): 97-101, 2001 Mar 01.

Article in En | MEDLINE | ID: mdl-11242049

Subject(s)

Aorta, Thoracic/pathology; DiGeorge Syndrome/pathology; T-Box Domain Proteins/genetics; Animals; Aorta, Thoracic/embryology; Cell Line; DiGeorge Syndrome/embryology; Gene Deletion; Gene Targeting; Haplotypes; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Mutagenesis; T-Box Domain Proteins/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Aorta, Thoracic / T-Box Domain Proteins / DiGeorge Syndrome Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Nature Year: 2001 Document type: Article Affiliation country: United States Country of publication: United kingdom

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