Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities.

Galbiati, F; Engelman, J A; Volonte, D; Zhang, X L; Minetti, C; Li, M; Hou, H; Kneitz, B; Edelmann, W; Lisanti, M P

Galbiati, F; Engelman, J A; Volonte, D; Zhang, X L; Minetti, C; Li, M; Hou, H; Kneitz, B; Edelmann, W; Lisanti, M P.

Affiliation

Galbiati F; Department of Molecular Pharmacology, Albert Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

J Biol Chem ; 276(24): 21425-33, 2001 Jun 15.

Article in En | MEDLINE | ID: mdl-11259414

Subject(s)

Caveolins/genetics; Caveolins/physiology; Dystrophin/metabolism; Animals; Calcium Channels, L-Type/analysis; Calcium Channels, L-Type/genetics; Caveolin 3; Caveolins/deficiency; Glycoproteins/metabolism; Humans; Membrane Microdomains/pathology; Membrane Microdomains/physiology; Mice; Mice, Knockout; Microtubules/pathology; Microtubules/physiology; Microtubules/ultrastructure; Muscle Proteins/deficiency; Muscle Proteins/genetics; Muscle Proteins/physiology; Muscle, Skeletal/metabolism; Muscle, Skeletal/pathology; Muscular Dystrophies/genetics; Muscular Dystrophy, Animal/genetics; Muscular Dystrophy, Animal/pathology; Mutation; Restriction Mapping; Ryanodine Receptor Calcium Release Channel/analysis; Ryanodine Receptor Calcium Release Channel/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Dystrophin / Caveolins Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2001 Document type: Article Affiliation country: United States

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