Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice.

Ozaki, M; Deshpande, S; Angkeow, P; Bellan, J; Lowenstein, C J; Dinauer, M C; Goldschmidt-Clermont, P; Suzuki, S; Irani, K

Ozaki, M; Deshpande, S; Angkeow, P; Bellan, J; Lowenstein, C J; Dinauer, M C; Goldschmidt-Clermont, P; Suzuki, S; Irani, K.

Affiliation

Ozaki M; Department of Surgical Research, National Children's Hospital, Tokyo, Japan.

Transplant Proc ; 33(1-2): 863-4, 2001.

Article in En | MEDLINE | ID: mdl-11267105

Subject(s)

Liver/blood supply; Reactive Oxygen Species/metabolism; Reperfusion Injury/prevention & control; Transfection; rac1 GTP-Binding Protein/antagonists & inhibitors; Adenoviridae/genetics; Animals; Apoptosis; Enzyme Induction; Lipid Peroxidation; Liver/enzymology; Liver/pathology; Mice; Mice, Inbred C57BL; NF-kappa B/metabolism; Necrosis; Reperfusion Injury/enzymology; Reperfusion Injury/pathology; rac1 GTP-Binding Protein/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Transfection / Reperfusion Injury / Reactive Oxygen Species / Rac1 GTP-Binding Protein / Liver Limits: Animals Language: En Journal: Transplant Proc Year: 2001 Document type: Article Affiliation country: Japan Country of publication: United States

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