Modulation of ligand responses by coupling of alpha(2A)-adrenoceptors to diverse G(alpha)-proteins.

Pauwels, P J; Tardif, S; Colpaert, F C; Wurch, T

Pauwels, P J; Tardif, S; Colpaert, F C; Wurch, T.

Affiliation

Pauwels PJ; Department of Cellular and Molecular Biology, Centre de Recherche Pierre Fabre, 17 Avenue Jean Moulin, F-81106, Castres Cédex, France. peter.pauwels@pierre-fabre.com

Biochem Pharmacol ; 61(9): 1079-92, 2001 May 01.

Article in En | MEDLINE | ID: mdl-11301041

Subject(s)

Adrenergic alpha-Agonists/pharmacology; Heterotrimeric GTP-Binding Proteins/metabolism; Receptors, Adrenergic, alpha-2/metabolism; Analysis of Variance; Animals; Azepines/pharmacology; CHO Cells; Cricetinae; GTP-Binding Protein alpha Subunits, Gq-G11; Guanosine 5'-O-(3-Thiotriphosphate)/metabolism; Heterotrimeric GTP-Binding Proteins/genetics; Medetomidine/pharmacology; Mutagenesis; Radioligand Assay; Recombinant Fusion Proteins/metabolism; Sulfur Radioisotopes

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Adrenergic, alpha-2 / Adrenergic alpha-Agonists / Heterotrimeric GTP-Binding Proteins Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2001 Document type: Article Affiliation country: France

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