Hepatic glycogen synthesis is highly sensitive to phosphorylase activity: evidence from metabolic control analysis.

Aiston, S; Hampson, L; Gómez-Foix, A M; Guinovart, J J; Agius, L

Aiston, S; Hampson, L; Gómez-Foix, A M; Guinovart, J J; Agius, L.

Affiliation

Aiston S; Department of Diabetes, University of Newcastle upon Tyne, The Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.

J Biol Chem ; 276(26): 23858-66, 2001 Jun 29.

Article in En | MEDLINE | ID: mdl-11309391

Subject(s)

Hepatocytes/metabolism; Liver Glycogen/biosynthesis; Phosphorylases/metabolism; Adenosine Monophosphate/pharmacology; Adenoviridae/genetics; Amides/pharmacology; Animals; Cells, Cultured; Enzyme Inhibitors/pharmacology; Glucagon/pharmacology; Glucokinase/genetics; Glucokinase/metabolism; Glucose/pharmacology; Glycogen Synthase/genetics; Glycogen Synthase/metabolism; Hepatocytes/drug effects; Hepatocytes/enzymology; Indoles/pharmacology; Male; Phosphorylase b/antagonists & inhibitors; Phosphorylase b/metabolism; Phosphorylases/antagonists & inhibitors; Rats; Rats, Wistar; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Hepatocytes / Phosphorylases / Liver Glycogen Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2001 Document type: Article Affiliation country: United kingdom Country of publication: United States

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