Increase in beta-cell mass in transplanted porcine neonatal pancreatic cell clusters is due to proliferation of beta-cells and differentiation of duct cells.

Trivedi, N; Hollister-Lock, J; Lopez-Avalos, M D; O'Neil, J J; Keegan, M; Bonner-Weir, S; Weir, G C

Trivedi, N; Hollister-Lock, J; Lopez-Avalos, M D; O'Neil, J J; Keegan, M; Bonner-Weir, S; Weir, G C.

Affiliation

Trivedi N; Section of Islet Transplantation and Cell Biology, Joslin Diabetes Center, Boston, Massachusetts 02215, USA.

Endocrinology ; 142(5): 2115-22, 2001 May.

Article in En | MEDLINE | ID: mdl-11316779

Subject(s)

Islets of Langerhans Transplantation; Islets of Langerhans/cytology; Pancreatic Ducts/cytology; Animals; Animals, Newborn; Apoptosis; C-Peptide/analysis; Cell Differentiation; Cell Division; Diabetes Mellitus, Experimental/therapy; Insulin/analysis; Male; Mice; Swine; Transplantation, Heterologous

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Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Ducts / Islets of Langerhans Transplantation / Islets of Langerhans Limits: Animals Language: En Journal: Endocrinology Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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