Antinociceptive effect of a genomic herpes simplex virus-based vector expressing human proenkephalin in rat dorsal root ganglion.

Goss, J R; Mata, M; Goins, W F; Wu, H H; Glorioso, J C; Fink, D J

Goss, J R; Mata, M; Goins, W F; Wu, H H; Glorioso, J C; Fink, D J.

Affiliation

Goss JR; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

Gene Ther ; 8(7): 551-6, 2001 Apr.

Article in En | MEDLINE | ID: mdl-11319622

Subject(s)

Analgesia/methods; Enkephalins/genetics; Ganglia, Spinal/metabolism; Genetic Therapy/methods; Genetic Vectors/therapeutic use; Protein Precursors/genetics; Simplexvirus/genetics; Animals; Enkephalins/metabolism; Formaldehyde; Humans; Male; Naltrexone/pharmacology; Pain Measurement; Protein Precursors/metabolism; Rats; Rats, Wistar; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Precursors / Enkephalins / Genetic Therapy / Simplexvirus / Ganglia, Spinal / Genetic Vectors / Analgesia Limits: Animals / Humans / Male Language: En Journal: Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2001 Document type: Article Affiliation country: United States Country of publication: United kingdom

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