Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE*3-Leiden transgenic mice.

van Vlijmen, B J; Gerritsen, G; Franken, A L; Boesten, L S; Kockx, M M; Gijbels, M J; Vierboom, M P; van Eck, M; van De Water, B; van Berkel, T J; Havekes, L M

van Vlijmen, B J; Gerritsen, G; Franken, A L; Boesten, L S; Kockx, M M; Gijbels, M J; Vierboom, M P; van Eck, M; van De Water, B; van Berkel, T J; Havekes, L M.

Affiliation

van Vlijmen BJ; Department of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Leiden/Amsterdam Center for Drug Research, Leiden, the Netherlands.

Circ Res ; 88(8): 780-6, 2001 Apr 27.

Article in En | MEDLINE | ID: mdl-11325869

Subject(s)

Apolipoproteins E/genetics; Arteriosclerosis/genetics; Macrophages/metabolism; Tumor Suppressor Protein p53/deficiency; Animals; Aortic Valve/pathology; Apolipoprotein E3; Apoptosis; Arteriosclerosis/metabolism; Arteriosclerosis/pathology; Bone Marrow Transplantation; Cell Count; Diet, Atherogenic; Disease Models, Animal; Disease Progression; In Situ Nick-End Labeling; Macrophages/pathology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Necrosis; Severity of Illness Index; Spleen/pathology; T-Lymphocytes/metabolism; T-Lymphocytes/pathology; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Arteriosclerosis / Tumor Suppressor Protein p53 / Macrophages Limits: Animals Language: En Journal: Circ Res Year: 2001 Document type: Article Affiliation country: Netherlands

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