Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta.

Zhao, C; Takita, J; Tanaka, Y; Setou, M; Nakagawa, T; Takeda, S; Yang, H W; Terada, S; Nakata, T; Takei, Y; Saito, M; Tsuji, S; Hayashi, Y; Hirokawa, N

Zhao, C; Takita, J; Tanaka, Y; Setou, M; Nakagawa, T; Takeda, S; Yang, H W; Terada, S; Nakata, T; Takei, Y; Saito, M; Tsuji, S; Hayashi, Y; Hirokawa, N.

Affiliation

Zhao C; Department of Cell Biology and Anatomy, University of Tokyo, Hongo, Tokyo 113-0033, Japan.

Cell ; 105(5): 587-97, 2001 Jun 01.

Article in En | MEDLINE | ID: mdl-11389829

Subject(s)

Charcot-Marie-Tooth Disease/genetics; Kinesins/genetics; Microtubules/genetics; Molecular Motor Proteins/genetics; Mutation, Missense; Nerve Tissue Proteins/genetics; Amino Acid Sequence; Animals; Axonal Transport/genetics; Cells, Cultured; Charcot-Marie-Tooth Disease/metabolism; Chronic Disease; Hippocampus/cytology; Humans; Kinesins/analysis; Kinesins/metabolism; Mice; Mice, Inbred ICR; Mice, Knockout; Mice, Neurologic Mutants; Microscopy, Immunoelectron; Microtubules/chemistry; Molecular Motor Proteins/metabolism; Molecular Sequence Data; Mutagenesis, Insertional/physiology; Nerve Tissue Proteins/analysis; Nerve Tissue Proteins/metabolism; Neurons/metabolism; Neurons/ultrastructure; Synaptic Vesicles/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Charcot-Marie-Tooth Disease / Kinesins / Molecular Motor Proteins / Mutation, Missense / Microtubules / Nerve Tissue Proteins Limits: Animals / Humans Language: En Journal: Cell Year: 2001 Document type: Article Affiliation country: Japan

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