Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

Woo, E Y; Chu, C S; Goletz, T J; Schlienger, K; Yeh, H; Coukos, G; Rubin, S C; Kaiser, L R; June, C H

Woo, E Y; Chu, C S; Goletz, T J; Schlienger, K; Yeh, H; Coukos, G; Rubin, S C; Kaiser, L R; June, C H.

Affiliation

Woo EY; Department of Surgery, Abramson Family Cancer Research Institute, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA.

Cancer Res ; 61(12): 4766-72, 2001 Jun 15.

Article in En | MEDLINE | ID: mdl-11406550

Subject(s)

CD4 Antigens/immunology; CD4-Positive T-Lymphocytes/immunology; Carcinoma, Non-Small-Cell Lung/immunology; Lung Neoplasms/immunology; Ovarian Neoplasms/immunology; Receptors, Interleukin-2/immunology; CD3 Complex/biosynthesis; CD4 Antigens/biosynthesis; CD4-Positive T-Lymphocytes/metabolism; CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/metabolism; Carcinoma, Non-Small-Cell Lung/metabolism; Carcinoma, Non-Small-Cell Lung/pathology; Down-Regulation; Female; Humans; Interferon-gamma/biosynthesis; Interleukin-2/biosynthesis; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; Lymphocyte Activation/immunology; Lymphocytes, Tumor-Infiltrating/immunology; Neoplasm Staging; Ovarian Neoplasms/metabolism; Ovarian Neoplasms/pathology; Receptors, Antigen, T-Cell/biosynthesis; Receptors, Interleukin-2/biosynthesis; Th1 Cells/immunology; Th1 Cells/metabolism; Transforming Growth Factor beta/metabolism; Tumor Necrosis Factor-alpha/biosynthesis

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / CD4-Positive T-Lymphocytes / Receptors, Interleukin-2 / CD4 Antigens / Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Limits: Female / Humans Language: En Journal: Cancer Res Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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