N-glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N_hydroxy-PhIP by specific human UDP-glucuronosyltransferases.

Malfatti, M A; Felton, J S

Malfatti, M A; Felton, J S.

Affiliation

Malfatti MA; Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, PO Box 808, L-452, Livermore, CA 94551, USA.

Carcinogenesis ; 22(7): 1087-93, 2001 Jul.

Article in En | MEDLINE | ID: mdl-11408353

Subject(s)

Carcinogens/pharmacokinetics; Glucuronosyltransferase/metabolism; Imidazoles/pharmacokinetics; Pyridines/pharmacokinetics; Biotransformation; Cell Line; Chromatography, High Pressure Liquid; Humans; Microsomes/enzymology; Spectrometry, Mass, Electrospray Ionization

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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Carcinogens / Glucuronosyltransferase / Imidazoles Limits: Humans Language: En Journal: Carcinogenesis Year: 2001 Document type: Article Affiliation country: United States Country of publication: United kingdom

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