Lacto-N-fucopentaose III found on Schistosoma mansoni egg antigens functions as adjuvant for proteins by inducing Th2-type response.

Okano, M; Satoskar, A R; Nishizaki, K; Harn, D A

Okano, M; Satoskar, A R; Nishizaki, K; Harn, D A.

Affiliation

Okano M; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA. mokano@cc.okayama-u.ac.jp

J Immunol ; 167(1): 442-50, 2001 Jul 01.

Article in En | MEDLINE | ID: mdl-11418681

Subject(s)

Adjuvants, Immunologic/administration & dosage; Amino Sugars/administration & dosage; Amino Sugars/immunology; Antigens, Helminth/immunology; Oligosaccharides/immunology; Polysaccharides/administration & dosage; Polysaccharides/immunology; Schistosoma mansoni/immunology; Administration, Intranasal; Animals; Antibodies, Helminth/biosynthesis; Antigens, CD/biosynthesis; Antigens, Helminth/administration & dosage; B7-2 Antigen; Cytokines/biosynthesis; Dose-Response Relationship, Immunologic; Epitopes/immunology; Female; Glycoconjugates/administration & dosage; Glycoconjugates/immunology; Humans; Injections, Intraperitoneal; Leukocyte Common Antigens/biosynthesis; Lymphocytes/immunology; Lymphocytes/metabolism; Membrane Glycoproteins/biosynthesis; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nasal Mucosa/cytology; Nasal Mucosa/immunology; Nasal Mucosa/metabolism; Oligosaccharides/administration & dosage; Serum Albumin/administration & dosage; Serum Albumin/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Oligosaccharides / Polysaccharides / Schistosoma mansoni / Adjuvants, Immunologic / Amino Sugars / Antigens, Helminth Limits: Animals / Female / Humans Language: En Journal: J Immunol Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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