Subchronic sodium chlorate exposure in drinking water results in a concentration-dependent increase in rat thyroid follicular cell hyperplasia.

Hooth, M J; Deangelo, A B; George, M H; Gaillard, E T; Travlos, G S; Boorman, G A; Wolf, D C

Hooth, M J; Deangelo, A B; George, M H; Gaillard, E T; Travlos, G S; Boorman, G A; Wolf, D C.

Affiliation

Hooth MJ; Environmental Carcinogenesis Division, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.

Toxicol Pathol ; 29(2): 250-9, 2001.

Article in En | MEDLINE | ID: mdl-11421493

Subject(s)

Chlorates/toxicity; Thyroid Gland/drug effects; Animals; Dose-Response Relationship, Drug; Female; Hyperplasia/chemically induced; Hyperplasia/pathology; Male; Rats; Rats, Inbred F344; Thyroid Gland/pathology; Thyrotropin/blood; Thyroxine/blood; Time Factors; Triiodothyronine/blood; Water Supply

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Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Gland / Chlorates Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Pathol Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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