p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.

Mahyar-Roemer, M; Roemer, K

Mahyar-Roemer, M; Roemer, K.

Affiliation

Mahyar-Roemer M; Internal Medicine IV, Building 47, University of Saarland Medical School, D-66421 Homburg/Saar, Germany.

Oncogene ; 20(26): 3387-98, 2001 Jun 07.

Article in En | MEDLINE | ID: mdl-11423989

Subject(s)

Adenocarcinoma/pathology; Anticarcinogenic Agents/pharmacology; Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Butyrates/pharmacology; Colonic Neoplasms/pathology; Cyclins/physiology; Drug Resistance, Neoplasm; Neoplasm Proteins/physiology; Stilbenes/pharmacology; Toluene/analogs & derivatives; Tumor Suppressor Protein p53/physiology; Alleles; Amino Acid Chloromethyl Ketones/pharmacology; Apoptosis/physiology; Benzothiazoles; Cisplatin/pharmacology; Cyclin-Dependent Kinase Inhibitor p21; Cysteine Proteinase Inhibitors/pharmacology; Demecolcine/pharmacology; Doxorubicin/pharmacology; Etoposide/pharmacology; Fluorouracil/pharmacology; Gene Expression Regulation, Neoplastic/drug effects; Genes, p53; Humans; Intracellular Membranes/drug effects; Intracellular Membranes/physiology; Membrane Potentials/drug effects; Mitochondria/drug effects; Recombination, Genetic; Resveratrol; Thiazoles/pharmacology; Toluene/pharmacology; Tumor Cells, Cultured/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Stilbenes / Toluene / Butyrates / Adenocarcinoma / Tumor Suppressor Protein p53 / Anticarcinogenic Agents / Apoptosis / Cyclins / Colonic Neoplasms / Drug Resistance, Neoplasm Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2001 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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