Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain.

Karras, J G; Maier, M A; Lu, T; Watt, A; Manoharan, M

Karras, J G; Maier, M A; Lu, T; Watt, A; Manoharan, M.

Affiliation

Karras JG; Department of Molecular and Cellular Pharmacology, ISIS Pharmaceuticals, Incorporated, 2292 Faraday Avenue, Carlsbad, California 92008, USA.

Biochemistry ; 40(26): 7853-9, 2001 Jul 03.

Article in En | MEDLINE | ID: mdl-11425312

Subject(s)

Alternative Splicing/drug effects; Peptide Nucleic Acids/pharmacology; RNA Precursors/metabolism; Receptors, Interleukin/genetics; Receptors, Interleukin/metabolism; Animals; Base Sequence; Mice; Oligonucleotides, Antisense/chemical synthesis; Oligonucleotides, Antisense/pharmacology; Peptide Nucleic Acids/chemical synthesis; Receptors, Interleukin-5; Thionucleotides/chemical synthesis; Thionucleotides/pharmacology; Transfection; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: RNA Precursors / Alternative Splicing / Receptors, Interleukin / Peptide Nucleic Acids Limits: Animals Language: En Journal: Biochemistry Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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