Dose-response study of recombinant factor VIIa/tissue factor inhibitor recombinant nematode anticoagulant protein c2 in prevention of postoperative venous thromboembolism in patients undergoing total knee replacement.

Lee, A; Agnelli, G; Büller, H; Ginsberg, J; Heit, J; Rote, W; Vlasuk, G; Costantini, L; Julian, J; Comp, P; van Der Meer, J; Piovella, F; Raskob, G; Gent, M

Lee, A; Agnelli, G; Büller, H; Ginsberg, J; Heit, J; Rote, W; Vlasuk, G; Costantini, L; Julian, J; Comp, P; van Der Meer, J; Piovella, F; Raskob, G; Gent, M.

Affiliation

Lee A; Hamilton Civic Hospitals Research Centre, McMaster University, Hamilton, Ontario, Canada.

Circulation ; 104(1): 74-8, 2001 Jul 03.

Article in En | MEDLINE | ID: mdl-11435341

Subject(s)

Anticoagulants/administration & dosage; Arthroplasty, Replacement, Knee; Factor VIIa/antagonists & inhibitors; Helminth Proteins/administration & dosage; Postoperative Complications/prevention & control; Venous Thrombosis/prevention & control; Aged; Arthroplasty, Replacement, Knee/adverse effects; Canada; Dose-Response Relationship, Drug; Europe; Female; Helminth Proteins/adverse effects; Hemorrhage/chemically induced; Humans; Injections, Subcutaneous; Logistic Models; Male; Odds Ratio; Risk Assessment; Survival Rate; Thromboplastin/antagonists & inhibitors; United States; Venous Thrombosis/etiology

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Collection: 01-internacional Database: MEDLINE Main subject: Postoperative Complications / Factor VIIa / Helminth Proteins / Arthroplasty, Replacement, Knee / Venous Thrombosis / Anticoagulants Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Country/Region as subject: America do norte / Europa Language: En Journal: Circulation Year: 2001 Document type: Article Affiliation country: Canada Country of publication: United States

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