Disruption of focal adhesions mediates detachment during neuronal apoptosis.

Lesay, A; Hickman, J A; Gibson, R M

Lesay, A; Hickman, J A; Gibson, R M.

Affiliation

Lesay A; School of Biological Sciences, 1.124 Stopford Building, University of Manchester, Manchester M13 9PT, UK.

Neuroreport ; 12(10): 2111-5, 2001 Jul 20.

Article in En | MEDLINE | ID: mdl-11447317

Subject(s)

Apoptosis/physiology; Extracellular Matrix/physiology; Focal Adhesions/physiology; Neurons/physiology; Proteins; Amino Acid Chloromethyl Ketones/pharmacology; Apoptosis/drug effects; Calpain/antagonists & inhibitors; Calpain/metabolism; Caspase Inhibitors; Caspases/metabolism; Cell Line; Cells, Cultured; Cysteine Proteinase Inhibitors/pharmacology; Cytoskeletal Proteins/metabolism; Dipeptides/pharmacology; Extracellular Matrix/drug effects; Extracellular Matrix/enzymology; Focal Adhesions/drug effects; Focal Adhesions/enzymology; Neurons/cytology; Neurons/drug effects; Neurons/enzymology; Paxillin; Phosphoproteins/metabolism; Retinoblastoma-Like Protein p130; Talin/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Apoptosis / Focal Adhesions / Extracellular Matrix / Neurons Language: En Journal: Neuroreport Journal subject: NEUROLOGIA Year: 2001 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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