Esters of chlorambucil with 2-substituted 1,4-dihydroxy-9,10-anthraquinones as multifunctional anticancer agents.

Jin, G Z; You, Y J; Kim, Y; Nam, N H; Ahn, B Z

Jin, G Z; You, Y J; Kim, Y; Nam, N H; Ahn, B Z.

Affiliation

Jin GZ; College of Pharmacy, Yanbian University, Yanji, Jilin 133000, People's Republic of China.

Eur J Med Chem ; 36(4): 361-6, 2001 Apr.

Article in En | MEDLINE | ID: mdl-11461761

Subject(s)

Anthraquinones/chemistry; Anthraquinones/pharmacology; Antineoplastic Agents/chemistry; Antineoplastic Agents/pharmacology; Chlorambucil/chemistry; Animals; Chlorambucil/pharmacology; Drug Screening Assays, Antitumor; Leukemia L1210; Male; Mice; Mice, Inbred ICR; Sarcoma, Experimental/drug therapy; Sarcoma, Experimental/mortality; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Chlorambucil / Anthraquinones / Antineoplastic Agents Limits: Animals Language: En Journal: Eur J Med Chem Year: 2001 Document type: Article Country of publication: France

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