Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites.

Horner, A A; Datta, S K; Takabayashi, K; Belyakov, I M; Hayashi, T; Cinman, N; Nguyen, M D; Van Uden, J H; Berzofsky, J A; Richman, D D; Raz, E

Horner, A A; Datta, S K; Takabayashi, K; Belyakov, I M; Hayashi, T; Cinman, N; Nguyen, M D; Van Uden, J H; Berzofsky, J A; Richman, D D; Raz, E.

Affiliation

Horner AA; Department of Medicine, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

J Immunol ; 167(3): 1584-91, 2001 Aug 01.

Article in En | MEDLINE | ID: mdl-11466380

Subject(s)

AIDS Vaccines/immunology; Adjuvants, Immunologic/administration & dosage; Anti-HIV Agents/administration & dosage; CpG Islands/immunology; Oligodeoxyribonucleotides/immunology; Vaccines, DNA/immunology; AIDS Vaccines/administration & dosage; AIDS Vaccines/chemical synthesis; AIDS Vaccines/genetics; Adjuvants, Immunologic/genetics; Administration, Intranasal; Animals; Anti-HIV Agents/chemical synthesis; Chemokines/metabolism; Cytokines/metabolism; Cytotoxicity, Immunologic/genetics; Female; H-2 Antigens; HIV Envelope Protein gp120/genetics; Immunity, Mucosal/genetics; Immunoglobulin A/biosynthesis; Immunoglobulin G/blood; Lymphocyte Activation/genetics; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides/administration & dosage; Oligodeoxyribonucleotides/chemical synthesis; T-Lymphocytes, Cytotoxic/immunology; Th1 Cells/immunology; Th1 Cells/metabolism; Vaccines, DNA/administration & dosage; Vaccines, DNA/chemical synthesis

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Collection: 01-internacional Database: MEDLINE Main subject: Oligodeoxyribonucleotides / Adjuvants, Immunologic / AIDS Vaccines / CpG Islands / Vaccines, DNA / Anti-HIV Agents Limits: Animals Language: En Journal: J Immunol Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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